Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.52 |
| ▸ | KDR | P35968 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866940 | 0.82 | HTT (0.58) | HTTMCHR1KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7868785 | 0.81 | HTT (0.57) | HTTMCHR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7867119 | 0.81 | HTT (0.60) | HTTKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL7862077 | 0.81 | HTT (0.63) | HTTKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL8015660 | 0.81 | HTT (0.54) | HTTKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL7868799 | 0.80 | HTT (0.58) | HTTKMT2AMEN1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7866960 | 0.80 | HTT (0.58) | HTTKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL7870660 | 0.78 | HTT (0.56) | HTTKMT2AMEN1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7867109 | 0.78 | HTT (0.56) | HTTHRH3MCHR1KDRKMT2A | |
| Hydrochloric Acid SCHEMBL7873984 | 0.78 | KDM4E (0.61) | HTTKMT2AMEN1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |