Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7868785 | 0.99 | HTT (0.57) | HTTALDH1A1KMT2AMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL8015362 | 0.89 | HTT (0.56) | HTTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL7868753 | 0.86 | ALDH1A1 (0.62) | HTTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL7867119 | 0.86 | HTT (0.60) | HTTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL7862077 | 0.86 | HTT (0.63) | HTTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL7866966 | 0.86 | BCAT2 (0.57) | HTTALDH1A1KMT2AMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL7862082 | 0.85 | ALDH1A1 (0.61) | HTTALDH1A1KMT2AMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL7868707 | 0.85 | BCAT2 (0.56) | HTTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL7868799 | 0.85 | HTT (0.58) | HTTALDH1A1KMT2AMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL7866960 | 0.85 | HTT (0.58) | HTTALDH1A1KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |