Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 6/20 | 0.46 |
| ▸ | MMP1 | P03956 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7868882 | 0.82 | HTT (0.49) | MMP13MMP1HTTNPSR1SLC1A3 | |
| Hydrochloric Acid SCHEMBL7208478 | 0.81 | MMP13 (0.57) | MMP13MMP1HTTNPSR1SLC1A3 | |
| Hydrochloric Acid SCHEMBL7207769 | 0.77 | HTT (0.55) | MMP13MMP1HTTNPSR1SLC1A3 | |
| SCHEMBL7862144 | 0.75 | MMP13 (0.48) | MMP13MMP1HTTNPSR1SLC1A3 | |
| Hydrochloric Acid SCHEMBL7862140 | 0.74 | MMP13 (0.47) | MMP13MMP1HTTNPSR1SLC1A3 | |
| Hydrochloric Acid SCHEMBL7862116 | 0.74 | MMP13 (0.59) | MMP13MMP1HTTNPSR1MEN1 | |
| SCHEMBL7207033 | 0.71 | MMP13 (0.56) | MMP13MMP1HTTNPSR1SLC1A3 | |
| SCHEMBL7077694 | 0.70 | MMP13 (0.63) | MMP13MMP1HTTNPSR1MEN1 | |
| SCHEMBL6378307 | 0.69 | HTT (0.59) | MMP13MMP1HTTNPSR1SLC1A3 | |
| SCHEMBL5125710 | 0.69 | MMP13 (0.46) | MMP13SLC1A3SLC1A2SLC1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | claimed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |