Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ME3 | Q16798 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14618675 | 0.87 | NAMPT (0.69) | KMT2AMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL13460461 | 0.85 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1MAPTNAMPT | |
| SCHEMBL3093740 | 0.85 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1MAPTNAMPT | |
| SCHEMBL27383392 | 0.85 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1MAPTNAMPT | |
| SCHEMBL30799179 | 0.85 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1MAPTNAMPT | |
| SCHEMBL9940282 | 0.84 | HPGD (0.69) | KMT2AMEN1ALDH1A1MAPTME3 | |
| SCHEMBL31198189 | 0.84 | PTPN1 (0.68) | KMT2AMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL9851155 | 0.82 | PTPN1 (0.77) | KMT2AMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL29057710 | 0.82 | PTPN1 (0.77) | KMT2AMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL3093727 | 0.82 | CYP2C9 (0.61) | KMT2AMEN1ALDH1A1MAPTNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |