SCHEMBL787007

SCHEMBL787007

CC(C)CC[Si](C)(C)O[Si](O[Si](C)(C)CCC(CC(=O)O)CC(=O)O)(O[Si](C)(C)CCC(CC(=O)O)CC(=O)O)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HPGD P15428 1/20 0.33
MMP12 P39900 1/20 0.32
LMNA P02545 1/20 0.32
PKM P14618 1/20 0.32
FFAR1 O14842 1/20 0.31
HTT P42858 1/20 0.31
POLB P06746 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13042904 0.95 MMP12 (0.34) MMP12FFAR1POLB
SCHEMBL15761478 0.85 FFAR1 (0.38) FFAR1ALDH1A1
SCHEMBL786860 0.84 NPC1 (0.30) SMN1; SMN2NPC1RAB9AL3MBTL1HPGD
SCHEMBL14586568 0.84 NPC1 (0.30) SMN1; SMN2NPC1RAB9AL3MBTL1HPGD
SCHEMBL786925 0.83 CACNA2D1 (0.39)
SCHEMBL13042932 0.78 MMP12 (0.31) MMP12
SCHEMBL13042907 0.76 CPA1 (0.41) MMP12
SCHEMBL13042911 0.76 CACNA2D1 (0.35) SMN1; SMN2
SCHEMBL13042868 0.73 CACNA2D1 (0.33)
SCHEMBL15761479 0.71 FFAR1 (0.33) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166342-A1 Functionalized Matrices for Dispersion of Nanostructures NANOSYS, INC. (US) 2015-06-18 US disclosed
US-20130043433-A1 Functionalized Matrixes for Dispersion of Nanostructures NANOSYS, INC. (US) 2013-02-21 US disclosed
US-20120068118-A1 NANOCRYSTAL DOPED MATRIXES SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120068118-A1 NANOCRYSTAL DOPED MATRIXES STRA6, EPHA6, PIR SMN1; SMN2 1562/4885NPC1 3609/4885RAB9A 1833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.