Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPS1 | P31327 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18010744 | 0.94 | CPS1 (0.57) | CPS1KMT2AEPHX2HRH4HTT | |
| SCHEMBL7878686 | 0.88 | CPS1 (0.60) | CPS1HTTLMNAMAPTTSHR | |
| SCHEMBL12205464 | 0.87 | CPS1 (0.58) | CPS1KMT2AHTTMEN1LMNA | |
| SCHEMBL18311852 | 0.85 | MEN1 (0.59) | CPS1KMT2AEPHX2HRH4HTT | |
| SCHEMBL17400790 | 0.85 | CPS1 (0.58) | CPS1KMT2AEPHX2HRH4MEN1 | |
| SCHEMBL1447752 | 0.85 | POLB (0.62) | CPS1KMT2AEPHX2HRH4MEN1 | |
| SCHEMBL7872416 | 0.82 | CPS1 (0.57) | CPS1KMT2AEPHX2HTTMEN1 | |
| SCHEMBL16994744 | 0.82 | TSHR (0.54) | CPS1HTTLMNAMAPTTSHR | |
| SCHEMBL12237783 | 0.81 | HTT (0.62) | CPS1KMT2AHRH4HTTMEN1 | |
| SCHEMBL13841322 | 0.81 | KDM4E (0.63) | CPS1KMT2AEPHX2HRH4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122069-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |