Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPS1 | P31327 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18010744 | 0.88 | CPS1 (0.57) | CPS1HTTTSHRLMNAMAPT | |
| SCHEMBL7878686 | 0.87 | CPS1 (0.60) | CPS1HTTTSHRLMNAMAPT | |
| SCHEMBL12205464 | 0.86 | CPS1 (0.58) | CPS1HTTTSHRLMNAMAPT | |
| SCHEMBL24910640 | 0.84 | LMNA (0.53) | HTTTSHRLMNAMAPTKDM4E | |
| SCHEMBL7878481 | 0.84 | ALDH1A1 (0.55) | CPS1HTTTSHRLMNAMAPT | |
| SCHEMBL7870107 | 0.84 | CPS1 (0.54) | CPS1HTTTSHRLMNAMAPT | |
| SCHEMBL17400772 | 0.83 | CPS1 (0.56) | CPS1HTTTSHRLMNAMAPT | |
| SCHEMBL7878741 | 0.83 | CPS1 (0.52) | CPS1HTTTSHRLMNAMAPT | |
| SCHEMBL7872429 | 0.83 | MAPT (0.57) | CPS1HTTTSHRLMNAMAPT | |
| SCHEMBL7870100 | 0.82 | CPS1 (0.59) | CPS1HTTTSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122069-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |