Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PNLIP | P16233 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18485496 | 0.94 | RARB (0.50) | RARBMAPK1MAPTTSHRALDH1A1 | |
| SCHEMBL6670588 | 0.94 | RARB (0.50) | RARBMAPK1MAPTTSHRALDH1A1 | |
| SCHEMBL5371346 | 0.94 | RARB (0.50) | RARBMAPK1MAPTTSHRALDH1A1 | |
| SCHEMBL7864542 | 0.94 | RARB (0.50) | RARBMAPK1MAPTTSHRALDH1A1 | |
| SCHEMBL5371350 | 0.94 | RARB (0.50) | RARBMAPK1MAPTTSHRALDH1A1 | |
| SCHEMBL6671767 | 0.94 | RARB (0.50) | RARBMAPK1MAPTTSHRALDH1A1 | |
| SCHEMBL6672236 | 0.94 | RARB (0.50) | RARBMAPK1MAPTTSHRALDH1A1 | |
| SCHEMBL7866970 | 0.94 | RARB (0.50) | RARBMAPK1MAPTTSHRALDH1A1 | |
| SCHEMBL7859268 | 0.93 | RARB (0.51) | RARBMAPK1MAPTGRIN2DGRIN2A | |
| SCHEMBL7864531 | 0.93 | RARB (0.51) | RARBMAPK1MAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811639-B1 | SOLID CATALYTIC COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST | TOHO TITANIUM CO LTD (JP) | 2001-08-01 | — | — | EP | disclosed |
| US-5965478-A | A POLYMERIZATION CATALYST IS A REACTION PRODUCT OF A TITANIUM HALIDE, A DIESTER OF AROMATIC DICARBOXYLIC ACID AND A DIALKOXYMAGNESIUM PARTICLES HAVING A HIGH BULK DENSITY; POLYOLEFIN HAVING A HIGH STEREOREGULARITY, HIGH BULK DENSITY | TOHO TITANIUM CO., LTD. (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0811639-A1 | SOLID CATALYTIC COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST | TOHO TITANIUM CO., LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |