Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 19/20 | 0.80 |
| ▸ | RARB | P10826 | 18/20 | 0.57 |
| ▸ | RARG | P13631 | 18/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870648 | 1.00 | RARA (0.80) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7811836 | 0.90 | RARA (0.65) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7811831 | 0.90 | RARA (0.65) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL29374587 | 0.89 | RARA (1.00) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL3690047 | 0.89 | RARA (1.00) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL3690042 | 0.89 | RARA (1.00) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7870645 | 0.86 | RARA (0.59) | RARARARBRARGRXRA | |
| SCHEMBL7800463 | 0.84 | RARA (0.85) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7800467 | 0.84 | RARA (0.85) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7811806 | 0.83 | RARA (0.83) | RARARARBRARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319948-B2 | PREVENTION AND/OR MINIMIZATION OF SURGICAL ADHESION FORMATION BY ADMINISTERING CERTAIN SUBSTITUTED (5,6)-DIHYDRONAPHTHALENYL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2001-11-20 | — | — | US | disclosed |