Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870788 | 1.00 | MAPK1 (0.38) | MAPK1GAAUSP2SMN1; SMN2HRH3 | |
| SCHEMBL18175908 | 0.86 | GAA (0.35) | MAPK1GAAUSP2SMN1; SMN2HRH3 | |
| SCHEMBL26181244 | 0.85 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL29988783 | 0.84 | USP2 (0.41) | MAPK1GAAUSP2SMN1; SMN2HCRTR2 | |
| Hydrochloric Acid SCHEMBL29356070 | 0.82 | USP2 (0.40) | MAPK1GAAUSP2SMN1; SMN2HCRTR2 | |
| SCHEMBL16097219 | 0.80 | CHRM2 (0.39) | MAPK1GAAUSP2SMN1; SMN2HRH3 | |
| SCHEMBL21125959 | 0.79 | MAPK1 (0.37) | MAPK1GAAUSP2SMN1; SMN2HRH3 | |
| SCHEMBL26413809 | 0.79 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL28056494 | 0.77 | HPGD (0.43) | GAASMN1; SMN2ALDH1A1KDM4ERECQL | |
| SCHEMBL15359968 | 0.77 | HPGD (0.43) | GAASMN1; SMN2ALDH1A1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |