Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 10/20 | 0.54 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787094 | 1.00 | NOD1 (0.54) | NOD1GNPATSLC6A5FOLH1RIMKLA | |
| SCHEMBL787096 | 1.00 | NOD1 (0.54) | NOD1GNPATSLC6A5FOLH1RIMKLA | |
| SCHEMBL8964448 | 0.88 | NOD1 (0.71) | NOD1SLC6A5 | |
| SCHEMBL20553085 | 0.88 | NOD1 (0.71) | NOD1SLC6A5 | |
| SCHEMBL928640 | 0.86 | GNPAT (0.47) | NOD1GNPATSLC6A5FOLH1RIMKLA | |
| SCHEMBL28378530 | 0.86 | NOD1 (0.59) | NOD1GNPATSLC6A5FOLH1RIMKLA | |
| SCHEMBL9752254 | 0.86 | NOD1 (0.74) | NOD1SLC6A5 | |
| SCHEMBL9752230 | 0.86 | NOD1 (0.74) | NOD1SLC6A5 | |
| SCHEMBL16190303 | 0.86 | NOD1 (0.74) | NOD1SLC6A5 | |
| SCHEMBL9752251 | 0.86 | NOD1 (0.74) | NOD1SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8350061-B2 | Synthetic analogs of bacterial quorum sensors | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2013-01-08 | — | — | US | disclosed |
| US-20120071430-A1 | SYNTHETIC ANALOGS OF BACTERIAL QUORUM SENSORS | LOS ALAMOS NATIONAL LABORATORY (US) | 2012-03-22 | — | — | US | disclosed |
| US-8071790-B2 | Synthetic analogs of bacterial quorum sensors | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110053890-A1 | SYNTHETIC ANALOGS OF BACTERIAL QUORUM SENSORS | LOS ALAMOS NATIONAL SECURITY, LLC. (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053890-A1 | SYNTHETIC ANALOGS OF BACTERIAL QUORUM SENSORS | QRFPR, COASY, Q6ZSR9 | NOD1 82/4885GNPAT 1250/4885SLC6A5 3580/4885 |
| US-20120071430-A1 | SYNTHETIC ANALOGS OF BACTERIAL QUORUM SENSORS | QRFPR, COASY, Q6ZSR9 | NOD1 82/4885GNPAT 1250/4885SLC6A5 3580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.