Biphenyl

Biphenyl

SCHEMBL7871061

CO.CP(C)C.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
SLC22A2 O15244 1/20 0.46
SLC22A1 O15245 1/20 0.46
SLC22A3 O75751 1/20 0.46
SLC6A4 P31645 1/20 0.46
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
MGLL Q99685 1/20 0.43
CYP1A2 P05177 2/20 0.43
MAPK1 P28482 1/20 0.43
CYP3A4 P08684 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NOTUM Q6P988 1/20 0.43
ALOX5 P09917 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7874616 0.90 ALDH1A1 (0.64) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL7865548 0.90 ALDH1A1 (0.64) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL4386499 0.90 ALDH1A1 (0.64) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL6828949 0.89 ALDH1A1 (0.75) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL2346762 0.89 ALDH1A1 (0.75) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL1133504 0.89 ALDH1A1 (0.75) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL8165523 0.87 ALDH1A1 (0.60) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL28832401 0.86 ALDH1A1 (0.69) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Tannin Pyrogallol SCHEMBL27842912 0.86 ALDH1A1 (0.69) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL7872988 0.85 SMN1; SMN2 (0.58) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed