Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.85 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.85 |
| ▸ | PTGES | O14684 | 2/20 | 0.85 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.85 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.85 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.85 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | DLAT | P10515 | 1/20 | 0.85 |
| ▸ | MAPT | P10636 | 1/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.85 |
| ▸ | ACHE | P22303 | 13/20 | 0.61 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98723 | 0.99 | SIRT2 (0.86) | SIRT2SIRT1PTGESSLC6A2SLC6A4 | |
| SCHEMBL12634392 | 0.99 | SIRT2 (0.86) | SIRT2SIRT1PTGESSLC6A2SLC6A4 | |
| SCHEMBL21907266 | 0.99 | SIRT2 (0.86) | SIRT2SIRT1PTGESSLC6A2SLC6A4 | |
| SCHEMBL14577497 | 0.99 | SIRT2 (0.86) | SIRT2SIRT1PTGESSLC6A2SLC6A4 | |
| SCHEMBL15694967 | 0.99 | SIRT2 (0.86) | SIRT2SIRT1PTGESSLC6A2SLC6A4 | |
| SCHEMBL14233249 | 0.99 | SIRT2 (0.86) | SIRT2SIRT1PTGESSLC6A2SLC6A4 | |
| SCHEMBL7624217 | 0.98 | SIRT2 (0.85) | SIRT2SIRT1PTGESSLC6A2SLC6A4 | |
| Methoxymethane SCHEMBL7942622 | 0.96 | SIRT2 (0.82) | SIRT2SIRT1PTGESSLC6A2SLC6A4 | |
| SCHEMBL14837010 | 0.92 | SIRT2 (1.00) | SIRT2SIRT1PTGESSLC6A2SLC6A4 | |
| SCHEMBL8168239 | 0.92 | SIRT2 (1.00) | SIRT2SIRT1PTGESSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6322824-B1 | Use of hyperforin and hyperforin-containing extracts in the treatment of dementia diseases | WILLMAR SCHWABE GMBH & CO. (DE) | 2001-11-27 | — | — | US | disclosed |