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Methoxymethane

Methoxymethane

SCHEMBL7942622

CC(C)=CCC[C@]1(C)[C@@H](CC=C(C)C)C[C@]2(CC=C(C)C)C(=O)C(CC=C(C)C)=C(O)[C@@]1(C(=O)C(C)C)C2=O.COC

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SIRT2 Q8IXJ6 3/20 0.82
▸ SIRT1 Q96EB6 3/20 0.82
▸ PTGES O14684 2/20 0.82
▸ SLC6A2 P23975 2/20 0.82
▸ SLC6A4 P31645 2/20 0.82
▸ SLC6A3 Q01959 2/20 0.82
▸ NR1I2 O75469 1/20 0.82
▸ CYP3A4 P08684 1/20 0.82
▸ DLAT P10515 1/20 0.82
▸ MAPT P10636 1/20 0.82
▸ SMN1; SMN2 Q16637 1/20 0.82
▸ ACHE P22303 14/20 0.59
▸ STAT1 P42224 1/20 0.45
▸ POLL Q9UGP5 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12634392 0.97 SIRT2 (0.86) SIRT2SIRT1PTGESSLC6A2SLC6A4
SCHEMBL14577497 0.97 SIRT2 (0.86) SIRT2SIRT1PTGESSLC6A2SLC6A4
SCHEMBL21907266 0.97 SIRT2 (0.86) SIRT2SIRT1PTGESSLC6A2SLC6A4
SCHEMBL98723 0.97 SIRT2 (0.86) SIRT2SIRT1PTGESSLC6A2SLC6A4
SCHEMBL15694967 0.97 SIRT2 (0.86) SIRT2SIRT1PTGESSLC6A2SLC6A4
SCHEMBL14233249 0.97 SIRT2 (0.86) SIRT2SIRT1PTGESSLC6A2SLC6A4
SCHEMBL7624217 0.96 SIRT2 (0.85) SIRT2SIRT1PTGESSLC6A2SLC6A4
SCHEMBL7871338 0.96 SIRT2 (0.85) SIRT2SIRT1PTGESSLC6A2SLC6A4
SCHEMBL8168239 0.90 SIRT2 (1.00) SIRT2SIRT1PTGESSLC6A2SLC6A4
SCHEMBL14837010 0.90 SIRT2 (1.00) SIRT2SIRT1PTGESSLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000054785-A9 STABILIZED BICYCLO[3.3.1]NONENES AND METHODS OF USE SHAMAN PHARMACEUTICALS INC (US) 2001-12-27 — — WO disclosed
WO-2000054785-A2 STABILIZED BICYCLO[3.3.1]NONENES AND METHODS OF USE SHAMAN PHARMACEUTICALS, INC. (US) 2000-09-21 — — WO disclosed
WO-2000054760-A2 BICYCLO (3.3.1) NONENES USEFUL FOR THE TREATMENT OF DIABETES AND HYPERTRIGLYCERIDEMIA SHAMAN PHARMACEUTICALS, INC. (US) 2000-09-21 — — WO disclosed