Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.41 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876120 | 0.87 | AKR1C3 (0.50) | SLC9A1SLC9A3SLC9A2CYP3A4ALDH1A1 | |
| SCHEMBL4084710 | 0.85 | DHODH (0.49) | SLC9A1SLC9A3SLC9A2CYP3A4ALDH1A1 | |
| SCHEMBL31623020 | 0.85 | DHODH (0.49) | SLC9A1SLC9A3SLC9A2CYP3A4ALDH1A1 | |
| SCHEMBL4084715 | 0.85 | DHODH (0.49) | SLC9A1SLC9A3SLC9A2CYP3A4ALDH1A1 | |
| SCHEMBL9065444 | 0.82 | AKR1C3 (0.45) | SLC9A1SLC9A3SLC9A2ALDH1A1KDM4E | |
| SCHEMBL9065442 | 0.82 | AKR1C3 (0.45) | SLC9A1SLC9A3SLC9A2ALDH1A1KDM4E | |
| SCHEMBL9065964 | 0.79 | SLC9A1 (0.54) | SLC9A1SLC9A3SLC9A2CYP3A4ALDH1A1 | |
| SCHEMBL9065961 | 0.79 | SLC9A1 (0.54) | SLC9A1SLC9A3SLC9A2CYP3A4ALDH1A1 | |
| SCHEMBL7882297 | 0.79 | MAPT (0.44) | CYP3A4ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL5830527 | 0.78 | AKR1C3 (0.52) | SLC9A1SLC9A3SLC9A2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329546-B1 | FOR INVESTIGATING THE MECHANISM OF ACTION OF A PHYSIOLOGICALLY ACTIVE AMINO ACID COMPOUND SUCH AS GLUTAMIC ACID IN AN ORGANISM | LABORATORY OF MOLECULAR BIOPHOTONICS (JP) | 2001-12-11 | — | — | US | disclosed |