Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 5/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306276 | 0.82 | NOS2 (0.39) | NOS2NOS3NOS1DPP4PRCP | |
| Hydrochloric Acid SCHEMBL28244170 | 0.81 | NOS2 (0.38) | NOS2NOS3NOS1DPP4PRCP | |
| SCHEMBL7331648 | 0.78 | NOS2 (0.36) | NOS2NOS3NOS1DPP4 | |
| SCHEMBL10686210 | 0.78 | NOS2 (0.36) | NOS2NOS3NOS1DPP4 | |
| SCHEMBL1358236 | 0.77 | NOS2 (0.43) | NOS2NOS3NOS1DPP4PRCP | |
| SCHEMBL26117510 | 0.76 | NOS2 (0.41) | NOS2NOS3NOS1DPP4PRCP | |
| SCHEMBL27313673 | 0.76 | SLC6A2 (0.38) | NOS2NOS3NOS1DPP4PRCP | |
| SCHEMBL27347264 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL28206791 | 0.74 | NOS2 (0.39) | NOS2NOS3NOS1DPP4PRCP | |
| Hydrochloric Acid SCHEMBL8976071 | 0.74 | NOS2 (0.36) | NOS2NOS3NOS1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310180-B1 | PEPTIDE BIOSYNTHESIS REQUIRING NEITHER PROTECTION NOR ACTIVE C-ALPHA CARBOXYL GROUPS BY COUPLING PEPTIDES BY REACTING A 1-AMINO-2-MERCAPTO ALKYL ATTACHED TO ONE PEPTIDE WITH THE CARBOXY GROUP OF THE OTHER; REARRANGEMENT; STABILITY | VANDERBILT UNIVERSITY | 2001-10-30 | — | — | US | disclosed |