Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552293 | 0.89 | KMT2A (0.52) | KMT2AEPHX2OPRD1CASP3 | |
| SCHEMBL2414302 | 0.80 | KMT2A (0.43) | KMT2AEPHX2 | |
| SCHEMBL5557644 | 0.79 | KMT2A (0.60) | KMT2AEPHX2IDO1CASP3 | |
| SCHEMBL6032374 | 0.79 | KMT2A (0.67) | KMT2AEPHX2OPRD1CASP3 | |
| SCHEMBL29625033 | 0.77 | KMT2A (0.65) | KMT2AEPHX2IDO1CASP3 | |
| SCHEMBL13631378 | 0.77 | KMT2A (0.65) | KMT2AEPHX2IDO1CASP3 | |
| SCHEMBL732427 | 0.77 | KMT2A (0.68) | KMT2AEPHX2IDO1 | |
| SCHEMBL6209235 | 0.77 | KMT2A (0.56) | KMT2AEPHX2OPRD1 | |
| SCHEMBL32671446 | 0.76 | KMT2A (0.51) | KMT2ANAMPTEPHX2CASP3 | |
| SCHEMBL14485472 | 0.76 | KMT2A (0.51) | KMT2ANAMPTEPHX2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306854-B1 | ARYLTHIOALKYLACIDS AND ALKYL UREAS | GLAXOSMITHKLINE | 2001-10-23 | — | — | US | disclosed |