Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.46 |
| ▸ | PPARA | Q07869 | 10/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871527 | 1.00 | PPARG (0.46) | PPARGPPARAFFAR1CYP3A4CYP2C9 | |
| SCHEMBL9286066 | 0.89 | PPARG (0.47) | PPARGPPARAFFAR1CYP3A4CYP2C9 | |
| SCHEMBL7879128 | 0.89 | PPARG (0.47) | PPARGPPARAFFAR1CYP3A4CYP2C9 | |
| SCHEMBL7877637 | 0.89 | PPARG (0.47) | PPARGPPARAFFAR1CYP3A4CYP2C9 | |
| SCHEMBL9274342 | 0.89 | PPARG (0.47) | PPARGPPARAFFAR1CYP3A4CYP2C9 | |
| SCHEMBL7877640 | 0.89 | PPARG (0.47) | PPARGPPARAFFAR1CYP3A4CYP2C9 | |
| SCHEMBL4283015 | 0.84 | PPARG (0.63) | PPARGPPARACYP3A4CYP2C9KCNH2 | |
| SCHEMBL170065 | 0.84 | PPARG (0.63) | PPARGPPARACYP3A4CYP2C9KCNH2 | |
| SCHEMBL9721218 | 0.84 | PPARG (0.55) | PPARGPPARA | |
| Darglitazone SCHEMBL37497 | 0.82 | PPARG (0.48) | PPARGPPARAFFAR1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329408-B1 | HYPOCHOLESTEROLEMIC AGENTS; OPTICALLY PURE | PFIZER INC. | 2001-12-11 | — | — | US | disclosed |