SCHEMBL7871571

SCHEMBL7871571

CCOC(=O)N1CCC1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.57
GAA P10253 1/20 0.43
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
THRB P10828 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ELANE P08246 1/20 0.40
CTSG P08311 1/20 0.40
ACE P12821 4/20 0.39
REN P00797 2/20 0.39
LMNA P02545 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 1/20 0.39
F2 P00734 1/20 0.39
LTA4H P09960 1/20 0.39
MAPT P10636 1/20 0.39
PEPD P12955 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25414655 1.00 RAB9A (0.57) RAB9AGAAALDH1A1SMN1; SMN2THRB
SCHEMBL3172593 0.89 RAB9A (0.71) RAB9AALDH1A1SMN1; SMN2L3MBTL1ACE
SCHEMBL7406144 0.89 RAB9A (0.71) RAB9AALDH1A1SMN1; SMN2L3MBTL1ACE
SCHEMBL3172600 0.89 RAB9A (0.71) RAB9AALDH1A1SMN1; SMN2L3MBTL1ACE
SCHEMBL9668555 0.87 RAB9A (0.65) RAB9AALDH1A1SMN1; SMN2ACEREN
SCHEMBL395833 0.87 RAB9A (0.65) RAB9AALDH1A1SMN1; SMN2ACEREN
Hydrochloric Acid SCHEMBL28049456 0.87 RAB9A (0.69) RAB9AALDH1A1SMN1; SMN2L3MBTL1ACE
Hydrochloric Acid SCHEMBL27968384 0.87 RAB9A (0.69) RAB9AALDH1A1SMN1; SMN2L3MBTL1ACE
SCHEMBL4748923 0.84 RAB9A (0.50) RAB9AALDH1A1SMN1; SMN2ATML3MBTL1
SCHEMBL7672219 0.84 RAB9A (0.50) RAB9AALDH1A1SMN1; SMN2ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313315-B1 RESOLUTION; ENANTIOMORPHIC PURIFICATION; CRYSTALLIZATION IN SOLVENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-06 US disclosed
EP-1057810-A1 Method for producing n-protected-azetidine-2-carboxylic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-12-06 EP disclosed