Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20558558 | 0.92 | TSHR (0.39) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL28854521 | 0.88 | TSHR (0.43) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL17468410 | 0.84 | TDP1 (0.41) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL29133102 | 0.83 | TSHR (0.39) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL25786776 | 0.82 | TDP1 (0.39) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL10976267 | 0.80 | TDP1 (0.38) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL25786842 | 0.80 | TDP1 (0.38) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL11214675 | 0.80 | TSHR (0.46) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL28525347 | 0.80 | TSHR (0.46) | TSHRALDH1A1TDP1GRIN2DGRIN3B | |
| SCHEMBL9358618 | 0.80 | TSHR (0.46) | TSHRALDH1A1TDP1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137645-A2 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034260-A2 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |