Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.34 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646968 | 0.90 | TSHR (0.43) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11214675 | 0.90 | TSHR (0.46) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8086687 | 0.87 | TSHR (0.44) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28378850 | 0.86 | ALDH1A1 (0.38) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4603509 | 0.85 | TSHR (0.43) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4603550 | 0.85 | TSHR (0.43) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20558558 | 0.84 | TSHR (0.39) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9361805 | 0.84 | TSHR (0.39) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28051270 | 0.84 | TSHR (0.52) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9358618 | 0.84 | TSHR (0.46) | TSHRALDH1A1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112368255-A | Preparation method of halogenated polyfluorobenzene | 谢尔盖·米哈伊洛维奇·伊古诺夫 | 2021-02-12 | — | — | CN | disclosed |