Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7880354 | 0.84 | ATM (0.40) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5164925 | 0.83 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL21694054 | 0.76 | TSHR (0.65) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28476200 | 0.75 | TSHR (0.58) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL321925 | 0.74 | TSHR (0.85) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL244114 | 0.74 | TSHR (0.95) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL691866 | 0.74 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL11552072 | 0.74 | TSHR (0.69) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL1585542 | 0.74 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL4958348 | 0.74 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331373-B1 | CHARGE STABILITY AND FLUIDITY | NIPPON SHOKUBAI CO., LTD. (JP) | 2001-12-18 | — | — | US | disclosed |