Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864740 | 1.00 | HCAR2 (0.40) | HCAR2GRIN2BS1PR5MEN1KMT2A | |
| SCHEMBL7864737 | 1.00 | HCAR2 (0.40) | HCAR2GRIN2BS1PR5MEN1KMT2A | |
| SCHEMBL7873412 | 1.00 | HCAR2 (0.40) | HCAR2GRIN2BS1PR5MEN1KMT2A | |
| SCHEMBL9179049 | 0.83 | HCAR2 (0.44) | HCAR2GRIN2BS1PR5MEN1KMT2A | |
| SCHEMBL1667289 | 0.77 | HCAR2 (0.41) | HCAR2GRIN2BMEN1KMT2ASCN3A | |
| SCHEMBL1667292 | 0.74 | HCAR2 (0.40) | HCAR2GRIN2BMEN1KMT2ASCN3A | |
| SCHEMBL27904989 | 0.74 | HCAR2 (0.51) | HCAR2GRIN2BS1PR5S1PR1KCNH2 | |
| SCHEMBL1665342 | 0.71 | HCAR2 (0.49) | HCAR2GRIN2BHSD17B10L3MBTL1RECQL | |
| SCHEMBL7873893 | 0.71 | POLB (0.48) | HCAR2GRIN2BS1PR5MEN1KMT2A | |
| SCHEMBL2034468 | 0.71 | HCAR2 (0.45) | HCAR2GRIN2BKCNH2SCN3ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313095-B1 | HERPES VIRAL RIBONUCLEOTIDE REDUCTASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 2001-11-06 | — | — | US | claimed |
| EP-0411333-B1 | Antiherpes tetrapeptide derivatives having a substituted aspartic acid side chain | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-05-31 | — | — | EP | claimed |
| US-6313095-B1 | HERPES VIRAL RIBONUCLEOTIDE REDUCTASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 2001-11-06 | — | — | US | disclosed |
| EP-0411333-B1 | Antiherpes tetrapeptide derivatives having a substituted aspartic acid side chain | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-05-31 | — | — | EP | disclosed |