Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207430 | 1.00 | HSD17B10 (0.44) | HSD17B10NR1H2ELANEACESMN1; SMN2 | |
| SCHEMBL1782216 | 1.00 | HSD17B10 (0.44) | HSD17B10NR1H2ELANEACESMN1; SMN2 | |
| SCHEMBL8353685 | 1.00 | HSD17B10 (0.44) | HSD17B10NR1H2ELANEACESMN1; SMN2 | |
| SCHEMBL13305759 | 1.00 | HSD17B10 (0.44) | HSD17B10NR1H2ELANEACESMN1; SMN2 | |
| SCHEMBL5207425 | 1.00 | HSD17B10 (0.44) | HSD17B10NR1H2ELANEACESMN1; SMN2 | |
| SCHEMBL7876562 | 1.00 | HSD17B10 (0.44) | HSD17B10NR1H2ELANEACESMN1; SMN2 | |
| SCHEMBL1782218 | 1.00 | HSD17B10 (0.44) | HSD17B10NR1H2ELANEACESMN1; SMN2 | |
| SCHEMBL24113374 | 0.99 | HSD17B10 (0.45) | HSD17B10NR1H2ELANEACESMN1; SMN2 | |
| SCHEMBL25362467 | 0.99 | HSD17B10 (0.45) | HSD17B10NR1H2ELANEACESMN1; SMN2 | |
| SCHEMBL3700523 | 0.93 | HSD17B10 (0.45) | HSD17B10NR1H2ELANESMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329502-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OF AIDS (ACQUIRED IMMUNE DEFICIENCY SYNDROME) | JAPAN ENERGY CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0490667-B1 | HIV protease inhibitors | JAPAN ENERGY CORP (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0490667-A2 | HIV protease inhibitors | JAPAN ENERGY CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |