Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | RARG | P13631 | 4/20 | 0.44 |
| ▸ | RARA | P10276 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872240 | 1.00 | RARB (0.44) | RARBRARGRARAAPPCYP26A1 | |
| SCHEMBL7879935 | 0.84 | RARB (0.60) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL7879932 | 0.84 | RARB (0.60) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL7872246 | 0.83 | CYP3A4 (0.43) | RARBRARGRARAAPPCYP26A1 | |
| SCHEMBL7872249 | 0.83 | CYP3A4 (0.43) | RARBRARGRARAAPPCYP26A1 | |
| SCHEMBL7879878 | 0.77 | RARB (0.52) | RARBRARGRARACYP26A1MAPT | |
| SCHEMBL7879873 | 0.77 | RARB (0.52) | RARBRARGRARACYP26A1MAPT | |
| SCHEMBL7876471 | 0.74 | RARB (0.52) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL7876428 | 0.74 | RARB (0.74) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL7876472 | 0.74 | RARB (0.52) | RARBRARGRARACYP26A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |