Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.52 |
| ▸ | RARG | P13631 | 7/20 | 0.52 |
| ▸ | RARA | P10276 | 6/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | RXRA | P19793 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879878 | 1.00 | RARB (0.52) | RARBRARGRARACYP26A1AKR1B10 | |
| SCHEMBL9551719 | 0.84 | RARB (0.54) | RARBRARGRARACYP26A1KMT2A | |
| SCHEMBL7876430 | 0.84 | RARB (0.74) | RARBRARGRARACYP26A1LMNA | |
| SCHEMBL7876428 | 0.84 | RARB (0.74) | RARBRARGRARACYP26A1LMNA | |
| SCHEMBL7876472 | 0.81 | RARB (0.52) | RARBRARGRARACYP26A1LMNA | |
| SCHEMBL7876471 | 0.81 | RARB (0.52) | RARBRARGRARACYP26A1LMNA | |
| SCHEMBL8839024 | 0.81 | KMT2A (0.56) | RARBRARGRARACYP26A1KMT2A | |
| SCHEMBL8839111 | 0.80 | KMT2A (0.52) | RARBRARGRARAKMT2ALMNA | |
| SCHEMBL8839103 | 0.80 | RXRA (0.52) | RARBRARGRARACYP26A1KMT2A | |
| SCHEMBL7086116 | 0.80 | RARG (0.67) | RARBRARGRARACYP26A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |