Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 4/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Palmitate SCHEMBL7802437 | 0.93 | LMNA (0.79) | LMNAMAPTMAPK1KDM4EDUSP3 | |
| Isopropyl Myristate SCHEMBL5157367 | 0.93 | LMNA (0.79) | LMNAMAPTMAPK1KDM4EDUSP3 | |
| SCHEMBL494127 | 0.87 | LMNA (0.83) | LMNAMAPTMAPK1PRKCAPRKCE | |
| SCHEMBL494007 | 0.87 | LMNA (0.83) | LMNAMAPTMAPK1PRKCAPRKCE | |
| SCHEMBL495050 | 0.87 | LMNA (0.83) | LMNAMAPTMAPK1PRKCAPRKCE | |
| SCHEMBL9216453 | 0.87 | LMNA (0.83) | LMNAMAPTMAPK1PRKCAPRKCE | |
| SCHEMBL12132118 | 0.87 | LMNA (0.83) | LMNAMAPTMAPK1PRKCAPRKCE | |
| SCHEMBL10788600 | 0.87 | LMNA (0.83) | LMNAMAPTMAPK1PRKCAPRKCE | |
| SCHEMBL494255 | 0.87 | LMNA (0.83) | LMNAMAPTMAPK1PRKCAPRKCE | |
| SCHEMBL495594 | 0.87 | LMNA (0.83) | LMNAMAPTMAPK1PRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0965342-B1 | PREPARATION FOR PERCUTANEOUS ADMINISTRATION CONTAINING 6-AMINO-5-CHLORO-1-ISOPROPYL-2-(4-METHYL-1-PIPERAZINYL)BENZIMIDAZOLE | NITTO DENKO CORP (JP) | 2001-08-08 | — | — | EP | disclosed |