SCHEMBL7872365

SCHEMBL7872365

CC1CC(N=C=O)CCC1N=C=O.O=C=NCC1CCCCC1CN=C=O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL452847 0.83 ALDH1A1 (0.41) ALDH1A1
SCHEMBL2340481 0.82 ALDH1A1 (0.35) ALDH1A1CYP3A4
SCHEMBL8530619 0.80 ALDH1A1 (0.36) ALDH1A1CYP3A4
SCHEMBL10606453 0.79 ALDH1A1 (0.35) ALDH1A1CYP3A4
SCHEMBL571423 0.74 ALDH1A1 (0.40) ALDH1A1
SCHEMBL302555 0.74 ALDH1A1 (0.39) ALDH1A1
SCHEMBL3890936 0.73 ALDH1A1 (0.32) ALDH1A1
SCHEMBL31347765 0.72 ALDH1A1 (0.38) ALDH1A1
SCHEMBL17302381 0.72 CA1 (0.34) ALDH1A1
SCHEMBL7763834 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849268-B1 Polycyclic iminooxadiazindiones from (cyclo)aliphatic 1,4-diisocyanates BAYER AG (DE) 2001-10-10 EP disclosed
EP-0849268-A1 Polycyclic iminooxadiazindiones from (cyclo)aliphatic 1,4-diisocyanates BAYER AG (DE) 1998-06-24 EP disclosed