Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736174 | 1.00 | DPP4 (0.42) | DPP4DPP8DPP9OPRD1 | |
| SCHEMBL5735632 | 0.89 | DPP4 (0.42) | DPP4DPP8DPP9OPRD1 | |
| SCHEMBL5736670 | 0.88 | DPP4 (0.47) | DPP4DPP8DPP9OPRD1 | |
| SCHEMBL7872449 | 0.86 | DPP4 (0.41) | DPP4DPP8DPP9OPRD1 | |
| SCHEMBL5736168 | 0.86 | DPP4 (0.41) | DPP4DPP8DPP9OPRD1 | |
| SCHEMBL5737130 | 0.84 | DPP4 (0.38) | DPP4DPP8DPP9OPRD1 | |
| SCHEMBL5744641 | 0.81 | OPRD1 (0.39) | DPP4DPP8DPP9OPRD1 | |
| SCHEMBL5735624 | 0.81 | DPP4 (0.40) | DPP4DPP8DPP9OPRD1 | |
| SCHEMBL5736663 | 0.80 | DPP4 (0.43) | DPP4DPP8DPP9OPRD1 | |
| SCHEMBL5733385 | 0.80 | DPP4 (0.40) | DPP4DPP8DPP9OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319902-B1 | TO ACTIVATE THE CENTRAL NERVOUS SYSTEM, SUCH AS, FOR EXAMPLE, SUSTAINED ACETYLCHOLINE RELEASING ACTION, ANTI-RESERPINE ACTION AND LOCOMOTOR INCREMENT | SHIONOGI & CO., LTD. (JP) | 2001-11-20 | — | — | US | disclosed |
| EP-0933379-A1 | NOVEL PEPTIDE DERIVATIVES HAVING THIAZOLYL-ALANINE RESIDUE | SHIONOGI & CO., LTD. (JP) | 1999-08-04 | — | — | EP | disclosed |