Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972568 | 0.80 | GRM5 (0.41) | GRM5 | |
| SCHEMBL8165987 | 0.80 | GRM5 (0.41) | GRM5 | |
| SCHEMBL7840974 | 0.76 | GRM5 (0.43) | GRM5PGRKCNH2 | |
| SCHEMBL6963296 | 0.76 | GRM5 (0.43) | GRM5PGRKCNH2 | |
| SCHEMBL2836304 | 0.76 | GRM5 (0.43) | GRM5PGRKCNH2 | |
| SCHEMBL7843744 | 0.73 | GRM5 (0.43) | GRM5 | |
| SCHEMBL6961269 | 0.73 | GRM5 (0.43) | GRM5 | |
| SCHEMBL7655571 | 0.69 | GRM5 (0.45) | GRM5PGRKCNH2 | |
| SCHEMBL14587413 | 0.69 | GRM5 (0.45) | GRM5PGRKCNH2 | |
| SCHEMBL5662057 | 0.69 | GRM5 (0.45) | GRM5PGRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319932-B1 | USEFUL FOR TREATING BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-11-20 | — | — | US | disclosed |
| WO-2000027827-A1 | OXAZOLIDINONES USEFUL AS ALPHA 1A ADRENOCEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-05-18 | — | — | WO | disclosed |