Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.40 |
| ▸ | UNG | P13051 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878854 | 0.89 | AKR1C3 (0.40) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7872552 | 0.89 | NR1H4 (0.50) | POLBSMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL8943333 | 0.80 | CYP3A4 (0.50) | POLBSMN1; SMN2MAPTMEN1KMT2A | |
| 4-Methylbenzoic Acid SCHEMBL6057207 | 0.80 | SMN1; SMN2 (0.68) | POLBPARP1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14406 | 0.80 | PARP1 (0.65) | POLBPARP1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL29382709 | 0.80 | PARP1 (0.65) | POLBPARP1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL142937 | 0.80 | PARP1 (0.65) | POLBPARP1SMN1; SMN2MAPTALDH1A1 | |
| Ethane SCHEMBL6533732 | 0.79 | MAPT (0.51) | POLBSMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL4393821 | 0.79 | MAPT (0.54) | POLBSMN1; SMN2MAPTALDH1A1MEN1 | |
| Toluene SCHEMBL28840552 | 0.78 | CYP3A4 (0.50) | POLBSMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316623-B1 | USEFUL FOR SCREENING IN BIOLOGICAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS | ISIS PHARMACEUTICALS, INC. | 2001-11-13 | — | — | US | disclosed |