Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28940131 | 0.82 | PTPN11 (0.47) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL28939848 | 0.81 | MAPT (0.57) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL28939840 | 0.78 | MAPK1 (0.45) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL8422973 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL28940138 | 0.78 | SMN1; SMN2 (0.57) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL18920930 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL7866130 | 0.76 | POLB (0.43) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL7861270 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL28939847 | 0.75 | ALDH1A1 (0.39) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL28940135 | 0.74 | CYP2A6 (0.42) | ALDH1A1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611868-A | Furanamide derivative and preparation method and application thereof | 山东大学 | 2023-01-17 | — | — | CN | claimed |
| CN-115611868-A | Furanamide derivative and preparation method and application thereof | 山东大学 | 2023-01-17 | — | — | CN | disclosed |
| US-6310092-B1 | TREATING SYSTEMIC LUPUS, MULTIPLE SCLEROSIS, RHEUMATOID ARTHRITIS, SEPTIC SHOCK, ERYTHEMA NODOSUM LEPROSY, SEPTICEMIA, UVEITIS, ADULT RESPIRATORY DISTRESS SYNDROME OR INFLAMMATORY BOWEL DISEASE | CENTAUR PHARMACEUTICALS, INC. | 2001-10-30 | — | — | US | disclosed |
| EP-1047683-A1 | THIOETHER FURAN NITRONE COMPOUNDS | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-11-02 | — | — | EP | disclosed |
| US-6127408-A | THIOETHER FURAN NITRONE COMPOUNDS; NERVOUS SYSTEM DEGENERATIVE DISORDERS, E.G. ALZHEIMER'S DISEASE; ANALYSIS OF FREE RADICALS BY FORMING ADDUCTS; INHIBIT THE FORMING OF A BETA(1-42) BETA-PLEATED SHEETS AND/OR SUPPRESSING CYTOKINES | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-10-03 | — | — | US | disclosed |
| US-5998469-A | NERVOUS SYSTEM DIOSRDERS; AUTOIMMUNE DISEASES; ANTIINFLAMMATORY AGENTS | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-12-07 | — | — | US | disclosed |
| WO-1999036415-A1 | THIOETHER FURAN NITRONE COMPOUNDS | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-07-22 | — | — | WO | disclosed |