SCHEMBL7872758

SCHEMBL7872758

CC(C(=O)O)([N+](=O)[O-])[N+](=O)[O-]

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TSHR P16473 4/20 0.40
TDP1 Q9NUW8 1/20 0.35
HIF1A Q16665 2/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
LMNA P02545 2/20 0.31
MEN1 O00255 1/20 0.31
BLM P54132 1/20 0.31
HBB P68871 1/20 0.31
KMT2A Q03164 1/20 0.31
GGT1 P19440 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16099341 0.80
SCHEMBL27853892 0.77 ALDH1A1 (0.43) ALDH1A1TSHRTDP1HIF1ACYP2D6
SCHEMBL5593709 0.77
Potassium Ion SCHEMBL11417826 0.74 ALDH1A1 (0.41) ALDH1A1TSHRTDP1CA5ACA5B
Hydrochloric Acid SCHEMBL11628111 0.74 ALDH1A1 (0.41) ALDH1A1TSHRTDP1HIF1ACYP2D6
SCHEMBL510250 0.72
SCHEMBL19283840 0.70 ALDH1A1 (0.38) ALDH1A1TSHRTDP1
SCHEMBL28876219 0.70 ALDH1A1 (0.38) ALDH1A1TSHRTDP1
SCHEMBL11776563 0.69 TSHR (0.39) ALDH1A1TSHRTDP1HIF1ACA5A
SCHEMBL28195472 0.69 TSHR (0.39) ALDH1A1TSHRTDP1HIF1ACA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107353951-B A kind of diesel cetane-number improver 湖北航天化学技术研究所 2019-03-01 CN claimed
CN-107353951-A A kind of diesel cetane-number improver 湖北航天化学技术研究所 2017-11-17 CN claimed
CN-107353951-B A kind of diesel cetane-number improver 湖北航天化学技术研究所 2019-03-01 CN disclosed
CN-107353951-A A kind of diesel cetane-number improver 湖北航天化学技术研究所 2017-11-17 CN disclosed
CN-105121401-A Method for producing nitroalkanes in a microstructured reactor BASF SE 2015-12-02 CN disclosed
US-6310093-B1 ADMINISTERING, IN AMOUNT EFFECTIVE TO REDUCE DAMAGE TO NEURONAL CELLS, COMPOUND WHICH SELECTIVELY INHIBITS EXTRACELLULAR GLUTAMINASE RELATIVE TO GLUTAMINASE PRESENT IN INTACT CELLS AND IS IMPERMEABLE TO INTACT CELL MEMBRANES ELAN PHARMACEUTICALS, INC. 2001-10-30 US disclosed
US-4910322-A Synthesis of geminal dinitro compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1990-03-20 US disclosed
US-4774366-A Synthesis of geminal dinitro compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1988-09-27 US disclosed
US-4594430-A Synthesis of geminal dinitro compounds UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1986-06-10 US disclosed