Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869799 | 0.92 | PARP1 (0.42) | GAAPARP1PRKAA2PRKAB2PRKAG1 | |
| SCHEMBL7868154 | 0.88 | PARP1 (0.46) | PARP1PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL7869768 | 0.87 | PARP1 (0.46) | PARP1PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL7866455 | 0.87 | KCNH2 (0.47) | GAAPRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL7868110 | 0.87 | PARP1 (0.47) | PARP1PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL7873099 | 0.86 | PARP1 (0.45) | PARP1PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL7869108 | 0.85 | PRMT5 (0.46) | PARP1PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL7873041 | 0.84 | PARP1 (0.42) | PARP1PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL7861540 | 0.84 | PRKAA2 (0.53) | PARP1PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL8491991 | 0.84 | PARP1 (0.42) | PARP1PRKAA2PRKAB2PRKAG1PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306860-B1 | ANTIVIRAL ACTIVITIES AGAINST HEPATATIS B AS WELL AS HUMAN IMMUNODEFICIENCY VIRUS | DONG WHA PHARM. INC. CO., LTD. (KR) | 2001-10-23 | — | — | US | disclosed |
| WO-1999058526-A1 | NOVEL 2,5-PYRIDINEDICARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-11-18 | — | — | WO | disclosed |