Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868154 | 0.90 | PARP1 (0.46) | PARP1KDM4EL3MBTL1PRKAB2PRKAG1 | |
| SCHEMBL7873078 | 0.90 | PLA2G1B (0.45) | PARP1MAPK1PLA2G1BATG4BNPC1 | |
| SCHEMBL7869768 | 0.89 | PARP1 (0.46) | PARP1PLA2G1BATG4BKMT2AKDM4E | |
| SCHEMBL7873041 | 0.88 | PARP1 (0.42) | PARP1KDM4EPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL7873097 | 0.87 | GAA (0.45) | PARP1KDM4EL3MBTL1PRKAB2PRKAG1 | |
| SCHEMBL7861544 | 0.86 | NAMPT (0.41) | PARP1KDM4EL3MBTL1PRKAB2PRKAG1 | |
| SCHEMBL7861556 | 0.86 | PLA2G1B (0.49) | MAPK1PLA2G1BATG4BNPC1RAB9A | |
| SCHEMBL7873099 | 0.86 | PARP1 (0.45) | PARP1KDM4EPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL7861532 | 0.86 | NAMPT (0.44) | PARP1RAB9AKMT2AKDM4EPRKAB2 | |
| SCHEMBL7869108 | 0.85 | PRMT5 (0.46) | PARP1KMT2AL3MBTL1PRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306860-B1 | ANTIVIRAL ACTIVITIES AGAINST HEPATATIS B AS WELL AS HUMAN IMMUNODEFICIENCY VIRUS | DONG WHA PHARM. INC. CO., LTD. (KR) | 2001-10-23 | — | — | US | disclosed |
| WO-1999058526-A1 | NOVEL 2,5-PYRIDINEDICARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-11-18 | — | — | WO | disclosed |