Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565530 | 0.94 | GAA (0.59) | GAAHTTTSHRKMT2AALDH1A1 | |
| SCHEMBL27487510 | 0.89 | TSHR (0.55) | GAAHTTTSHRKMT2AALDH1A1 | |
| SCHEMBL20711670 | 0.89 | GAA (0.56) | GAAHTTTSHRKMT2AALDH1A1 | |
| SCHEMBL18072216 | 0.85 | GAA (0.57) | GAAHTTTSHRKMT2AALDH1A1 | |
| SCHEMBL243559 | 0.84 | TSHR (0.70) | GAAHTTTSHRKMT2AALDH1A1 | |
| SCHEMBL7477447 | 0.83 | TSHR (0.61) | GAAHTTTSHRKMT2AALDH1A1 | |
| SCHEMBL11336780 | 0.83 | TSHR (0.57) | GAAHTTTSHRKMT2AALDH1A1 | |
| SCHEMBL1535633 | 0.82 | GAA (0.61) | GAAHTTTSHRKMT2AALDH1A1 | |
| SCHEMBL24430225 | 0.80 | TSHR (0.49) | GAAHTTTSHRKMT2AALDH1A1 | |
| SCHEMBL14372130 | 0.80 | GAA (0.52) | GAAHTTTSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703220-B1 | Process for the preparation of N-oxyl hindered amine esters using tetraalkyl orthotitanate tranesterification catalysts | CIBA SC HOLDING AG (CH) | 2001-01-03 | — | — | EP | claimed |
| US-5574163-A | TRANSESTERIFICATION | CIBA-GEIGY CORPORATION (US) | 1996-11-12 | — | — | US | claimed |
| EP-0703220-A1 | Process for the preparation of N-oxyl hindered amine esters using tetraalkyl orthotitanate tranesterification catalysts | CIBA-GEIGY AG (CH) | 1996-03-27 | — | — | EP | claimed |
| EP-0703220-B1 | Process for the preparation of N-oxyl hindered amine esters using tetraalkyl orthotitanate tranesterification catalysts | CIBA SC HOLDING AG (CH) | 2001-01-03 | — | — | EP | disclosed |