Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533362 | 0.90 | TSHR (0.75) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL9591172 | 0.88 | TSHR (0.63) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL9371118 | 0.87 | TSHR (0.49) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL9400321 | 0.86 | TSHR (0.82) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL565530 | 0.85 | GAA (0.59) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL11336780 | 0.85 | TSHR (0.57) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL14497517 | 0.84 | TSHR (0.59) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL7873167 | 0.83 | GAA (0.54) | TSHRKMT2AGAAALDH1A1HTT | |
| SCHEMBL13554252 | 0.83 | TSHR (0.58) | TSHRKMT2AGAAALDH1A1ESR1 | |
| SCHEMBL19720351 | 0.83 | TSHR (0.58) | TSHRKMT2AGAAALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204473-A | O-substituted N-hydroxy hindered amine stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | claimed |
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | disclosed |
| US-5204473-A | O-substituted N-hydroxy hindered amine stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| US-5112890-A | Piperidine compound with oxygen bonded to ring nitrogen | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0309402-A1 | N-substituted hindered amine stabilizers | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |