Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 8/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158885 | 0.79 | POLB (0.57) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5987740 | 0.77 | POLB (0.65) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13626300 | 0.74 | POLB (0.61) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20738594 | 0.74 | POLB (0.61) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11692509 | 0.72 | POLB (0.60) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2231946 | 0.70 | POLB (0.57) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20738519 | 0.69 | ALDH1A1 (0.57) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14000285 | 0.69 | POLB (0.68) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL2479293 | 0.69 | POLB (0.56) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13774961 | 0.68 | ALDH1A1 (0.71) | POLBALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808303-B1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ASTRAZENECA AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |