Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491800 | 0.83 | PPARD (0.62) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL9445916 | 0.83 | PPARD (0.48) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL10963454 | 0.83 | PPARD (0.48) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL8920004 | 0.78 | PPARD (0.52) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL17750406 | 0.78 | PPARD (0.47) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL15532056 | 0.76 | PPARD (0.65) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL2991834 | 0.75 | PPARD (0.58) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL9445918 | 0.75 | PPARD (0.44) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL5001168 | 0.74 | PPARD (0.56) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL6726806 | 0.74 | PPARD (0.52) | PPARDTSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035303-A2 | A NOVEL PROCESS FOR SYNTHESIS OF RAMELTEON, AND KEY INTERMEDIATES FOR THE SYNTHESIS OF RAMELTEON | CIPLA LIMITED ET AL (IN) | 2012-03-22 | — | — | WO | disclosed |