Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SAT1 | P21673 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445991 | 0.95 | PPARD (0.43) | PPARDCA12CA1CA2CA9 | |
| SCHEMBL9445916 | 0.91 | PPARD (0.48) | PPARDCA12CA1CA2CA9 | |
| SCHEMBL11203182 | 0.79 | TSHR (0.52) | PPARDCA12CA1CA2CA9 | |
| SCHEMBL9445947 | 0.76 | ALDH1A1 (0.37) | PPARDCA12CA1CA2CA9 | |
| SCHEMBL28336971 | 0.76 | TSHR (0.48) | PPARDTSHRALDH1A1 | |
| SCHEMBL787331 | 0.75 | PPARD (0.50) | PPARDCA12CA1CA2CA9 | |
| SCHEMBL6930781 | 0.74 | PPARD (0.54) | PPARDCA12CA1CA2CA9 | |
| SCHEMBL734947 | 0.74 | PPARD (0.54) | PPARDCA12CA1CA2CA9 | |
| SCHEMBL19818738 | 0.74 | PPARD (0.52) | PPARDCA12CA1CA2CA9 | |
| SCHEMBL6255231 | 0.74 | CA12 (0.48) | CA12CA2CA9TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |