Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680284 | 0.88 | CYP2D6 (0.43) | CYP2D6MCHR1NPY5RACACBFAAH | |
| SCHEMBL4681946 | 0.86 | CYP2D6 (0.51) | CYP2D6MCHR1ACACBCHRM5 | |
| SCHEMBL4682240 | 0.84 | SIGMAR1 (0.40) | CYP2D6MCHR1NPY5RACACBNPC1 | |
| SCHEMBL4678895 | 0.84 | CYP2D6 (0.47) | CYP2D6MCHR1ACACBFAAHCHRM5 | |
| Hydrochloric Acid SCHEMBL4684973 | 0.83 | CYP2D6 (0.45) | CYP2D6MCHR1NPY5RACACBF2 | |
| SCHEMBL4683509 | 0.83 | CYP2D6 (0.51) | CYP2D6MCHR1ACACBCHRM5OGA | |
| SCHEMBL4679086 | 0.83 | CYP2D6 (0.70) | CYP2D6MCHR1ACACBF2PRSS1 | |
| SCHEMBL4679079 | 0.83 | CYP2D6 (0.70) | CYP2D6MCHR1ACACBF2PRSS1 | |
| SCHEMBL4680280 | 0.68 | CYP2D6 (0.68) | CYP2D6MCHR1ACACBFAAHSMN1; SMN2 | |
| SCHEMBL4680274 | 0.68 | CYP2D6 (0.68) | CYP2D6MCHR1ACACBFAAHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319920-B1 | MUSCARINIC RECEPTOR ANTAGONIST USED IN GASTROINTESTINAL, GENITOURINARY TRACT, RESPIRATORY TRACT, CARDIOVASCULAR SYSTEM, CENTRAL NERVOUS SYSTEM DISORDERS AND IN ANESTHESIOLOGY AND OPHTHALMOLOGY | SYNTEX (U.S.A.) LLC | 2001-11-20 | — | — | US | claimed |
| US-6319920-B1 | MUSCARINIC RECEPTOR ANTAGONIST USED IN GASTROINTESTINAL, GENITOURINARY TRACT, RESPIRATORY TRACT, CARDIOVASCULAR SYSTEM, CENTRAL NERVOUS SYSTEM DISORDERS AND IN ANESTHESIOLOGY AND OPHTHALMOLOGY | SYNTEX (U.S.A.) LLC | 2001-11-20 | — | — | US | disclosed |