SCHEMBL7873487

SCHEMBL7873487

O=C1CCC(Oc2ccc(O)cc2)CC1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.53
PARP10 Q53GL7 1/20 0.43
EPHX2 P34913 2/20 0.41
FAAH O00519 1/20 0.41
AADAC P22760 1/20 0.41
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ESR1 P03372 1/20 0.38
HRH1 P35367 1/20 0.36
GRIN1 Q05586 2/20 0.36
GRIN2B Q13224 2/20 0.36
LMNA P02545 1/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20455794 0.83 MEN1 (0.48) ESR2PARP10EPHX2FAAHAADAC
SCHEMBL16902836 0.83 MEN1 (0.48) ESR2PARP10EPHX2FAAHAADAC
SCHEMBL2016296 0.82 EPHX2 (0.43) PARP10EPHX2ALDH1A1TSHRHRH1
SCHEMBL18234087 0.81 HTR2A (0.42) PARP10EPHX2ALDH1A1MEN1KMT2A
SCHEMBL7660770 0.81 SMN1; SMN2 (0.51) PARP10EPHX2ALDH1A1TDP1
SCHEMBL5520546 0.81 SLC6A4 (0.51) PARP10EPHX2FAAHMEN1KMT2A
SCHEMBL6787348 0.81 EPHX2 (0.49) PARP10EPHX2FAAH
SCHEMBL146600 0.80 HRH1 (0.57) EPHX2HRH1
SCHEMBL10858201 0.79 PARP10 (0.58) ESR2PARP10EPHX2FAAHAADAC
SCHEMBL1837838 0.79 PARP10 (0.53) ESR2PARP10EPHX2FAAHAADAC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313351-B1 Process for producing alicyclic monoketones and process for producing alicyclic diketones HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2001-11-06 US disclosed