Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.43 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238814 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL7876588 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL197230 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL197231 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL7876596 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL29035113 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL3418559 | 0.98 | DPP4 (0.49) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL7383848 | 0.98 | DPP4 (0.49) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL18103704 | 0.98 | DPP4 (0.49) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL3418556 | 0.98 | DPP4 (0.49) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110885358-A | Vaccine for preventing tumor recurrence and metastasis and application method thereof | 浙江爱睦世医学科技有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-110885358-A | Vaccine for preventing tumor recurrence and metastasis and application method thereof | 浙江爱睦世医学科技有限公司 | 2020-03-17 | — | — | CN | disclosed |
| CN-101462996-B | Preparation of 4-cyclohexyl proline derivative | SHANGHAI INST PHARM INDUSTRY | 2011-04-20 | — | — | CN | disclosed |
| CN-101462996-A | Preparation of 4-cyclohexyl proline derivative | SHANGHAI INST PHARM INDUSTRY (CN) | 2009-06-24 | — | — | CN | disclosed |
| US-6329502-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OF AIDS (ACQUIRED IMMUNE DEFICIENCY SYNDROME) | JAPAN ENERGY CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0490667-B1 | HIV protease inhibitors | JAPAN ENERGY CORP (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0379063-B1 | Process for preparing (trans)-4-substituted-DL-proline derivatives | SQUIBB & SONS INC (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0490667-A2 | HIV protease inhibitors | JAPAN ENERGY CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |
| EP-0379063-A2 | Process for preparing (trans)-4-substituted-DL-proline derivatives | E.R. SQUIBB & SONS, INC. (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4937355-A | CYCLIZING PROTECTED AMINO ESTER WITH POTASSIUM AMIDE BASE, HYDROLYZING, REMOVING PROTECTIVE GROUP | E. R. SQUIBB & SONS, INC. (US) | 1990-06-26 | — | — | US | disclosed |