Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.43 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238814 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL7876588 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL197230 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL197231 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL7873502 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| SCHEMBL29035113 | 1.00 | DPP4 (0.50) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL3418559 | 0.98 | DPP4 (0.49) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL7383848 | 0.98 | DPP4 (0.49) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL18103704 | 0.98 | DPP4 (0.49) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL3418556 | 0.98 | DPP4 (0.49) | DPP4CYP1A2CYP2D6ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301260-B2 | Pyrrolidine GPR40 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-05-28 | — | — | US | disclosed |
| US-20170081282-A1 | PYRROLIDINE GPR40 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2017-03-23 | — | — | US | disclosed |
| US-6329502-B1 | VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OF AIDS (ACQUIRED IMMUNE DEFICIENCY SYNDROME) | JAPAN ENERGY CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6313094-B1 | COMPOSITION FOR INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | JAPAN ENERGY CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0490667-B1 | HIV protease inhibitors | JAPAN ENERGY CORP (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0490667-A2 | HIV protease inhibitors | JAPAN ENERGY CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081282-A1 | PYRROLIDINE GPR40 MODULATORS | GPR55, GPR65, GPR4 | DPP4 1321/4885CYP1A2 2003/4885CYP2D6 1569/4885 |
| US-10301260-B2 | Pyrrolidine GPR40 modulators | GPR55, GPR65, GPR4 | DPP4 1321/4885CYP1A2 2003/4885CYP2D6 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.