Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FKBP4 | Q02790 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Homoserine Lactone SCHEMBL28275156 | 0.98 | CA1 (0.48) | CA1CA9ALDH1A1LMNATP53 | |
| SCHEMBL2423922 | 0.88 | ALDH1A1 (0.46) | CA1CA9ALDH1A1LMNATP53 | |
| SCHEMBL3715777 | 0.86 | CA1 (0.52) | CA1CA9ALDH1A1LMNATP53 | |
| Homoserine Lactone SCHEMBL79466 | 0.83 | — | — | |
| Homoserine Lactone SCHEMBL79968 | 0.83 | — | — | |
| Homoserine Lactone SCHEMBL79969 | 0.83 | — | — | |
| SCHEMBL731550 | 0.83 | TSHR (0.32) | ALDH1A1LMNATP53TSHR | |
| SCHEMBL3661549 | 0.82 | ALDH1A1 (0.42) | CA1CA9ALDH1A1LMNATP53 | |
| Homoserine Lactone SCHEMBL1147212 | 0.81 | — | — | |
| Homoserine Lactone SCHEMBL7217249 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8350061-B2 | Synthetic analogs of bacterial quorum sensors | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2013-01-08 | — | — | US | disclosed |
| US-20120071430-A1 | SYNTHETIC ANALOGS OF BACTERIAL QUORUM SENSORS | LOS ALAMOS NATIONAL LABORATORY (US) | 2012-03-22 | — | — | US | disclosed |
| US-8071790-B2 | Synthetic analogs of bacterial quorum sensors | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110053890-A1 | SYNTHETIC ANALOGS OF BACTERIAL QUORUM SENSORS | LOS ALAMOS NATIONAL SECURITY, LLC. (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053890-A1 | SYNTHETIC ANALOGS OF BACTERIAL QUORUM SENSORS | QRFPR, COASY, Q6ZSR9 | CA1 4052/4885CA9 1249/4885ALDH1A1 4198/4885 |
| US-20120071430-A1 | SYNTHETIC ANALOGS OF BACTERIAL QUORUM SENSORS | QRFPR, COASY, Q6ZSR9 | CA1 4052/4885CA9 1249/4885ALDH1A1 4198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.