Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189991 | 0.83 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL7514399 | 0.82 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL7514397 | 0.82 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL4194390 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL4189266 | 0.81 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL4184799 | 0.81 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL4192966 | 0.81 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL4186885 | 0.80 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL7524046 | 0.78 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL4180279 | 0.78 | PTGS2 (0.67) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307047-B1 | PYRIDAZINONE COMPOUNDS; INHIBITORS OF CYCLOOXYGENASE-2 (COX-2); SELECTIVITY OF THESE COMPOUNDS FOR COX-2 MINIMIZES THE UNWANTED GI AND RENAL SIDE-EFFECTS SEEN WITH CURRENTLY MARKETED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ABBOTT LABORATORIES | 2001-10-23 | — | — | US | disclosed |