Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758849 | 0.89 | ALDH1A1 (0.33) | ALDH1A1HSD17B10LMNACYP2E1TSHR | |
| SCHEMBL6750515 | 0.82 | — | — | |
| SCHEMBL7637473 | 0.82 | — | — | |
| SCHEMBL14722550 | 0.82 | — | — | |
| SCHEMBL288 | 0.82 | — | — | |
| SCHEMBL27896 | 0.82 | — | — | |
| SCHEMBL8132063 | 0.82 | — | — | |
| SCHEMBL29105 | 0.82 | — | — | |
| SCHEMBL14785538 | 0.82 | — | — | |
| SCHEMBL8466155 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309345-B1 | SURFACE MODIFIED POLYMERIC MATERIAL ARTICLE WITH AN IMPROVED HEMOCOMPATIBILITY AN LOWER THROMBOGENICITY, AND METHOD FOR MAKING THE SAME | INSTITUT DE RECHERCHE APPLIQUEE SUR LES POLYMERES (I.R.A.P.) (FR) | 1993-09-22 | — | — | EP | claimed |
| EP-0907402-B1 | METHOD OF REMOVING, FROM A STREAM OF GAS, FLUORINATED COMPOUNDS WHICH CONTRIBUTE TO DESTRUCTION OF THE OZONE LAYER AND/OR CHANGES IN CLIMATE, AND USE OF THE METHOD | CS CLEAN SYSTEMS AG (DE) | 2001-05-23 | — | — | EP | disclosed |