Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 4/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.33 |
| ▸ | SELE | P16581 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879496 | 0.93 | SCN9A (0.35) | SLC6A4SLC6A2SCN9ASUCNR1BRAF | |
| SCHEMBL7884304 | 0.92 | SUCNR1 (0.32) | SUCNR1BRAFICAM1SELE | |
| SCHEMBL7878053 | 0.90 | SLC6A4 (0.40) | SLC6A4SLC6A2SCN9ABRAFSLC6A3 | |
| SCHEMBL7882381 | 0.89 | SLC6A4 (0.40) | SLC6A4SLC6A2BRAFICAM1SELE | |
| SCHEMBL7877628 | 0.88 | F10 (0.39) | SLC6A4SLC6A2SCN9ASUCNR1BRAF | |
| SCHEMBL7881879 | 0.88 | ICAM1 (0.32) | BRAFICAM1SELERHEBVCAM1 | |
| SCHEMBL7873734 | 0.87 | DYRK1A (0.34) | SLC6A4SCN9A | |
| SCHEMBL7873817 | 0.85 | SLC6A4 (0.37) | SLC6A4SLC6A2SCN9ASUCNR1BRAF | |
| SCHEMBL7884681 | 0.84 | SMN1; SMN2 (0.43) | SCN9ASUCNR1BRAFICAM1SELE | |
| SCHEMBL7880729 | 0.84 | FFAR1 (0.35) | SLC6A4SLC6A2SCN9ABRAFRHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248772-B1 | HYPOTENSIVE AGENTS; ANTIARRHYTHMIA AGENTS; ANTIDIABETIC AGENTS; ANTIPROLIFERATIVE AGENTS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6169107-B1 | USEFUL FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY INCREASED SODIUM/PROTON (NA.SUP.+ /H.SUP.+) EXCHANGER ACTIVITY, FOR EXAMPLE, HYPERTENSION, ARRHYTHMIA, ANGINA PECTORIS, CARDIAC HYPERTROPHY, DIABETES MELLITUS | SUMITOMO PHARMACEUTICAL CO., LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| EP-0708091-A2 | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |