Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7868842 | 0.99 | MCHR1 (0.48) | MCHR1HTR2CALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL7870706 | 0.88 | MCHR1 (0.48) | MCHR1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7874129 | 0.86 | MCHR1 (0.48) | MCHR1HTR2CALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL7870771 | 0.85 | MCHR1 (0.48) | MCHR1HTR2CALDH1A1LMNAMAPT | |
| SCHEMBL7869889 | 0.84 | PTK2 (0.43) | MCHR1ALDH1A1LMNAMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL7862227 | 0.83 | PTK2 (0.43) | MCHR1ALDH1A1LMNAMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL7867070 | 0.81 | MAPT (0.44) | MCHR1ALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL7869909 | 0.81 | SMN1; SMN2 (0.52) | MCHR1HTR2CLMNAMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL7869929 | 0.80 | SMN1; SMN2 (0.51) | MCHR1HTR2CLMNAMAPTTP53 | |
| SCHEMBL8003660 | 0.79 | NPSR1 (0.50) | MCHR1HTR2CLMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |