Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7869929 | 0.99 | SMN1; SMN2 (0.51) | SMN1; SMN2MCHR1MAPTTP53HTR2C | |
| SCHEMBL7869917 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2MCHR1MAPTTP53TSHR | |
| Hydrochloric Acid SCHEMBL7874146 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2MCHR1MAPTTP53TSHR | |
| SCHEMBL7866910 | 0.87 | ALDH1A1 (0.49) | SMN1; SMN2MCHR1MAPTTP53TSHR | |
| SCHEMBL7866953 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTTP53TSHRRAB9A | |
| Hydrochloric Acid SCHEMBL7862199 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTTP53TSHRRAB9A | |
| SCHEMBL8003660 | 0.83 | NPSR1 (0.50) | SMN1; SMN2MCHR1MAPTHTR2CRAB9A | |
| Hydrochloric Acid SCHEMBL7874098 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTTP53TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL7870801 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2MCHR1MAPTKDM4ERAB9A | |
| SCHEMBL11390594 | 0.81 | FAAH (0.52) | SMN1; SMN2MCHR1HTR2CKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |